The WLA Research Conference on Cells and Genes

  • Venue:

    WLA Shanghai Center (Shanghai Science Hall), Shanghai, China

  • Format:

    1.5-day, single-stream, on-site symposium

  • Date:

    July 27 - 28, 2023

  • Participants Limit:

    200 (advanced online registration + on-site registration required)

  • Registration Fee:

    $200 + Banquet fee $50 (optional)

  • Background

    The WLA Laboratories (WLA Labs) is an independent, nonprofit research institute committed to basic research and fostering the next generation of scientific talents. Scheduled to be inaugurated this July, the WLA Labs has planned a series of academic events, including the WLA Research Conferences (WRC). As an annual symposium of the WLA Labs, the WRC will create an open and interactive platform for scientists worldwide to freely discuss the most recent scientific discoveries and research findings. Each year, the conference will bring together experts in different areas of life science around the world, focusing on topics of current interest and debate. 

  • Overview

    The 2023 WLA Research Conference on Cells and Genes will take place on July 27 – 28, 2023, in Shanghai, and is hosted by the WLA Shanghai Center and organized by the WLA Labs. The chairs of this meeting are Prof. Roger Kornberg of Stanford University and Prof. James Rothman of Yale University. Prof. Kornberg wins the 2006 Nobel Prize in Chemistry for his work on "the molecular basis of eukaryotic transcription", whereas Prof. Rothman shares the 2013 Nobel Prize in Physiology or Medicine with Prof. Randy Schekman and Prof. Thomas Südhof for his work on "how messages are transmitted inside and outside our cells." Their fundamental research has inspired many important advancements in genetics and cell biology.


    The 2023 conference will feature frontier researchers in molecular and cell biology, structural biology, epigenetics, subcellular imaging, and related areas of biotechnology. It will have 5 plenary sessions, each for 90 minutes with 3 invited speakers. The conference highly encourages the latest unpublished results. Recording, photos, and videos are not permitted during the conference.

Scientific Panel

  • Prof. Roger Kornberg, Chair

    2006 Nobel Laureate in Chemistry

    Stanford University, U.S.A.

  • Prof. James Rothman, Co-Chair

    2013 Nobel Laureate in Physiology or Medicine

    Yale University, U.S.A.

  • Prof. Wolfgang Baumeister

    Max Planck Institute of Biochemistry, Germany

  • Prof. Chuan He (何川)

    2023 Wolf Prize Laureate in Chemistry

    The University of Chicago / HHMI, U.S.A.

  • Prof. Steven McKnight

    UT Southwestern Medical Center, U.S.A.

  • Prof. Carol Robinson

    Kavli Institute for Nanoscience Discovery, University of Oxford, UK

  • Prof. Yigong Shi (施一公)

    Westlake University, China

Organizing Committee

  • Guang Yang

    (杨 光), Ph.D.

    WLA Labs

  • Ernesto Carafoli, Ph.D.

     

    University of Padua, Italy

  • Xiaohong Helena Yang

    (杨晓虹), Ph.D.

    WLA Labs / WLA Shanghai Center

  • Xingxu Huang

    (黄行许), Ph.D.

    WLA Labs

  • Weidong Li

    (李卫东), Ph.D.

    Shanghai Jiao Tong University

  • Qiang Wu

    (吴 强), Ph.D.

    Shanghai Jiao Tong University

  • Ms. Ning Ma

    (马 宁), MBA

    WLA Labs

  • Ms. Yuhui Pei

    (裴育慧), M.A.

    WLA Labs / WLA Shanghai Center

Agenda

The WLA Research Conference on Cells and Genes
  • Date and Venue

    July 26, 2023 (UTC+8)

    WLA Shanghai Center (Shanghai Science Hall), Shanghai, China

  • 14:00-20:00 PM

    Registration and Check-in (Shanghai Science Hall)

  • 14:00-16:30 PM

    WLA Labs Tour

  • 17:30-19:30 PM

    Reception (All registered attendees, InterContinental Shanghai Ruijin)

The WLA Research Conference on Cells and Genes
  • Date and Venue

    July 27, 2023 (UTC+8)

    WLA Shanghai Center (Shanghai Science Hall), Shanghai, China

  • 08:00-08:45 AM

    Registration and Check-in

  • 09:00-09:15 AM

    Opening Remarks: Xiangdong Wu

    Executive Director, World Laureates Association;

    Chair, World Laureates Association Shanghai Center

  • 09:15-10:00 AM

    Keynote Speech: Turbocharging neurotransmitter release

    James Rothman, Ph.D., Sterling Professor of Cell Biology, Yale University

Session 1: Primitive Proteins

Chair: Steven McKnight

  • 10:00-10:30 AM

    Speaker #1 Steven McKnight

    How do protein domains of low sequence complexity work?

    Distinguished Chair in Basic Biomedical Research, Department of Biochemistry, UT Southwestern Medical Center

  • 10:30-11:00 AM

    Speaker #2 Dirk Görlich

    The FG phase – A smart material for controlling transport between the cell nucleus and the cytoplasm

    Scientific member and Director, Max Planck Institute for Multidisciplinary Sciences

  • 11:00-11:30 AM

    Speaker #3 Cong Liu 

    Protein amyloid aggregation in neurodegenerative diseases

    Principal investigator, Interdisciplinary Research Center on Biology and Chemistry (IRCBC), Chinese Academy of Sciences (CAS)

  • 11:30-11:45 AM

    Video: Lei Cai

    Scientists are the Hope of 500 Thousand ALS Patients' Lives

    Home of ALS Patients (HAP)

  • 11:45-13:00 PM

    Lunch Break

Session 2: Molecular Mechanisms Behind the Central Dogma

Chair:Yigong Shi

  • 13:00-13:30 PM

    Speaker #1 Yigong Shi

    Mechanism of RNA splicing by the spliceosome

    President, Westlake University

  • 13:30-14:00 PM

    Speaker #2 Yanhui Xu

    Structural insights into preinitiation complex assembly on chromatin

    Fudan University Shanghai Cancer Center, Institutes of Biomedical Sciences, Fudan University

  • 14:00-14:30 PM

    Speaker #3 Alexey Amunts

    How genes become machines in mitochondria

    Associate Professor, Science for Life Laboratory (SciLifeLab), Stockholm University

  • 14:30-16:00 PM

    Poster Session / Coffee Break

Session 3: Receptor Signaling Across Cell Membranes

Chair: Carol Robinson

  • 16:00-16:30 PM

    Speaker #1 Carol Robinson

    From recombinant complexes in detergent micelles to receptor signaling across native membranes – The promises and pitfalls of native mass spectrometry

    Dr. Lee's Professor of Chemistry, Director, Kavli Institute for Nanoscience Discovery, University of Oxford

  • 16:30-17:00 PM

    Speaker #2 Georgios Skiniotis

    Time-resolved cryoEM of G protein activation by a GPCR

    Professor of Molecular & Cellular Physiology, Professor of Structural Biology, Stanford University

  • 17:00-17:30 PM

    Speaker #3 Aashish Manglik

    Seeing Scents: Towards a structural basis of olfaction

    Associate Professor, Departments of Pharmaceutical Chemistry and Anesthesia, UC San Francisco

  • 18:30-20:30 PM

    Banquet (Registered guests only)

The WLA Research Conference on Cells and Genes
  • Date and Venue

    July 28, 2023 (UTC+8)

    WLA Shanghai Center (Shanghai Science Hall), Shanghai, China

Session 4: New Frontiers in RNA Biology

Chair: Chuan He

  • 09:00-09:30 AM

    Speaker #1 Chuan He

    Reversible RNA methylation in gene expression regulation

    John T. Wilson Distinguished Service Professor, The University of Chicago / HHMI

  • 09:30-10:00 AM

    Speaker #2 Xiao Wang

    Translating spatial cell atlas to tissue function

    Assistant Professor of Chemistry, MIT; Core member, The Broad Institute

  • 10:00-10:30 AM

    Speaker #3 Ling-Ling Chen

    Lnc-ing RNA processing and function

    Investigator, CAS Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences (CAS); New Cornerstone Science Laboratory

  • 10:30-11:00 AM

    Coffee Break

Session 5: Trends in Structural Biology

Chair: Wolfgang Baumeister

  • 11:00-11:30 AM

    Speaker #1 Wolfgang Baumeister

    Structural biology in situ: The promise and challenges of cryo-electron tomography

    Director, Max Planck Institute of Biochemistry

  • 11:30-12:00 PM
    (Noon)

    Speaker #2 Nenad Ban

    Revealing the remarkable machinery for production of proteins in human cells

    Professor of Structural Molecular Biology, ETH Zürich

  • 12:00-12:30 PM

    Speaker #3 Roger Kornberg

    Chromatin, chromosomes, and transcription

    Mrs. George A. Winzer Professor of Medicine, Stanford University

  • 12:30-12:45 PM

    Poster Prize Announcement: Prof. Ernesto Carafoli (University of Padua, ltaly)

  • 12:45-13:00 PM

    Closing Remarks: Prof. Roger Kornberg

Program
  1. Session 1:

    Primitive Proteins

    Chair: Steven McKnight

    July 27, 2023 / 10:00-11:30 A.M.

    READ MORE
  2. Session 2:

    Molecular Mechanisms Behind the Central Dogma

    Chair: Yigong Shi

    July 27, 2023 / 13:00-14:30 P.M.

    READ MORE
  3. Session 3:

    Receptor Signaling Across Cell Membranes

    Chair: Carol Robinson

    July 27, 2023 / 16:00-17:30 P.M.

    READ MORE
  4. Session 4:

    New Frontiers in RNA Biology

    Chair:Chuan He

    July 28, 2023 / 09:00-10:30 A.M.

    READ MORE
  5. Session 5:

    Trends in Structural Biology

    Chair:Wolfgang Baumeister

    July 28, 2023 / 11:00-12:30 P.M.

    READ MORE