Sign Up
公共头尾
-
Sign In
Thank you for signing up for the inaugural WLA Research Conference. Please read the following notice for a pleasant experience.
All participants need to register for the conference online at our official website and pay the registration fee and/or the banquet fee.
The registration fee is $200.00 per person and $50.00 per person for the banquet fee.
You can purchase up to 5 extra tickets with each having their contact information.
A full refund is available before July 20, 2020 (Beijing Time). After this date, refunds will not be provided.
You are welcome to bring your research poster and display at the Poster Session of WRC.
You are encouraged to read the Poster Presenter Guidelines to help you better prepare for the session.
The Best Poster Prize will be awarded at the closing of the meeting on July 28.
Please bring your ID document to pick up your badge and meeting materials at the Registration table on July 26, 2023, 10 am - 2 pm.
Please wear your badge during the meeting. Contact WLA Labs staff immediately if lost, and temporary one will be provided.
Meeting materials include a program book, a note pad, a pen and a WRC bag.
English is the working language of the meeting. No interpretation service is provided.
The venue of the meeting is La Salle Versailles, Shanghai Science Hall. You can take metro line 13, at Middle Huaihai Road, or drive here.
The parking lot is at right side of the building.
We recommend the following 2 premium hotels nearest to the meeting that can offer you a delightful experience:
a) Okura Garden Hotel Shanghai, five stars: No. 58, Maoming South Road
b) Intercontinental, five stars: No. 118, Ruijin 2nd Road
General inquiry, please contact info@wlalabs.com.cn.
In case of emergency, please contact 021-655 7670
Welcome to visit the World Laureates Association Laboratories (WLA Labs, hereinafter referred to as "We/us/our"). Thank you for choosing and accepting our services. The Term of Use (the "Agreement") is an agreement between you and the WLA Labs for the use of https://www.wrc.org.cn (the "Website") and/or mobile client, including registration, login, accessing certain content, uploading or otherwise submitting content and acceptance of related services.
1.1 In order to provide you with better services, please read the contents of this Agreement carefully. If you have any questions about the content of this Agreement or the information on the page, or do not agree with this Agreement, please do not proceed to the next step. If you click to confirm and start using our services, it means that you have fully understood this Agreement and agreed to be a party to this Agreement to accept all of the terms and conditions set forth in this Agreement and any other agreement or document incorporated herein by reference (including but not limited to the "Privacy Policy"). If you do not wish to accept the terms and conditions of this Agreement, PLEASE DO NOT proceed with the registration.
1.2 If you are a person without civil capacity or with limited civil capacity, please inform your guardian, and read this Agreement and use our services under the guidance of your guardian.
1.3 If you are not a user in the People's Republic of China (for the purpose of this Agreement, excluding Hong Kong S.A.R., Macau S.A.R., and Taiwan Region), you must also comply with the laws of your country or region, and you confirm that entering into and executing this Agreement does not violate the laws and regulations of the country or region where you belong, live, or conduct business activities or other businesses.
2.1 Website: refers to https://www.wrc.org.cn.
2.2 Account: refers to the login account that we open for you after you obtain the user ID and pass the identity verification. If you have not completed the identity verification, you cannot participate in the WLA Research Conference online or offline activities.
2.3 Personal information: refers to various information recorded electronically or in other forms that can identify a specific natural person independently or in combination with other information or reflect the activities of a specific natural person, including but not limited to the name, date of birth, ID number, email address, and contact information.
2.4. Identity elements: refers to the information elements we use to identify your identity, including but not limited to your user ID, login account number, password, SMS verification code, phone number and ID number.
2.5 Authorities: refers to entities that have the authority to request inquiries, suspending and other measures in accordance with laws and regulations, including but not limited to public security agencies, procuratorates, courts, customs, and tax agencies, etc.
3.1 When you accept our service, you need to complete the registration of the website account by submitting your name, mobile number and email address. If you need to buy tickets and participate in offline activities, you also need to provide us with personal information for citizen real-name verification, including your ID number, company, position, and personal photos. When you register and use our services, you should provide us with true, accurate, complete, legal, and valid information, and you are obliged to maintain and update your information in a timely manner.
3.2 You understand and promise that the account you set up shall not violate national laws and regulations and the provisions of this Agreement, your account name and other registration information shall not contain illegal or negative information, and you may not open an account in the name of another person without the permission of others. We shall have the right to review the information you submitted.
3.3 Your account is only for your own use. Without our written consent, it is prohibited to give, borrow, rent, transfer, sell or otherwise permit others to use the account in any form. If we find out or have reasonable grounds to believe that the user is not the initial registrant of the account, in order to protect the security of the account, we shall have the right to immediately suspend or terminate the provision of services to the registered account, or cancel the account.
3.4. You shall be responsible for maintaining the security of your personal accounts and passwords,shall not disclose your accounts and passwords to others under any circumstances, and assume full legal responsibility for the activities you engage in the name of the registered account. If you find that someone else uses your account without permission or any other security leaks occur, you shall notify us immediately.
3.5 After you complete the website account registration, log in and conduct reasonable and necessary identity verification, you can browse and modify the personal information submitted by yourself at any time. You understand and agree that for security and identification considerations, you may not be able to modify the initial registration information and other verification information provided during registration. You can also apply to cancel your account. We will assist you in canceling your account or deleting relevant data after completing reasonable and necessary verification such as verification of personal information, security status, and device information.
4.1. In order to provide you with better services, we may set up third-party links on our website. It is up to you to decide whether to access these links. We cannot guarantee the authenticity, accuracy, and reliability of the information provided by the third party. Any disputes or damages arising from third-party links have nothing to do with us, and we do not assume any responsibility.
4.2. When users use specific services provided by us (such as ticket purchases), we will support users' needs through third-party systems. When you use the services provided by a third party, in addition to complying with the provisions of this Agreement, you should also comply with the third party's user agreement.
You shall be responsible for your use of our services. If we have reason to believe that your behavior violates or may violate laws and regulations or this Agreement, we can independently judge and deal with it, and we shall have the right to terminate the provision of services to you without prior notice, and to pursue relevant legal liabilities. You must not commit the following acts when using the services we provide:
5.1 Produce, transmit, or publish any illegal or criminal information with a nature of intimidation, harassment, or slander against others;
5.2 Use any plug-in, tag-on service, system, or third-party tool that is not authorized or licensed by us to interfere, destroy, modify or otherwise affect the normal operation of related services;
5.3 Activities that endanger network security, such as illegal intrusion into the network, interference with normal network functions, and theft of network data;
5.4 Without permission, attempt to detect, scan, test the weakness of our system or network, or perform other behaviors that disrupt network security;
5.5 Reverse engineer, reverse assemble, compile, or otherwise attempt to discover the source code of our website or program;
5.6 Malicious registration of website accounts, including but not limited to frequent and bulk registration of accounts;
5.7 Commit other acts in violation of laws and regulations or this Agreement.
5.8 Publish, transmit, disseminate, or store content that violates the laws and regulations of the People's Republic of China, including but not limited to: violating the basic principles established by the Constitution; endangering national security, divulge state secrets, subvert state power and undermine national unity; damaging national honor and interest; inciting national hatred and ethnic discrimination, and destroy national unity; undermining national religious policies and promote cults and feudal superstition and any other content prohibited by the law and administrative regulations.
We fully respect and protect users' privacy and work with you to protect your personal information. During using this website, you may need to provide relevant personal information so that we can provide you with better services and corresponding technical support. We will use encryption technology, anonymization, and other technical measures that match the service and other security measures to protect your personal information. For more information about the protection of users' personal information, please refer to the "Privacy Policy."
If either party of this Agreement is unable to perform or fully perform the agreed obligations, the breaching party shall be liable for breach of contract. We are exempt from liability if we are unable to provide services normally due to the following reasons:
7.1 Our system is shut down for maintenance or upgrade;
7.2 Force majeure such as typhoon, earthquake, flood, lightning or terrorist attack;
7.3 The software and hardware, communication lines, or power supply lines of your electronic equipment are malfunctioning;
7.4 Your improper operation or using our services in a way that is not authorized or approved by us;
7.5 Viruses, Trojan, malicious program attacks, network congestion, system instability, system or equipment failures, communication failures, power failures, bank fault, third-party service defects, or government actions.
Notwithstanding the foregoing, we will take reasonable actions to actively promote the resumption of normal services.
8.1 We lawfully own the intellectual property rights, including but not limited to trademark rights, patent rights, copyrights, trade secrets, etc., embodied in works, pictures, files, information, materials, website structure, website page arrangement, website design.
8.2 Without our written consent, it is not permitted to use, modify, decompile, reproduce, publicly disseminate, change, distribute, issue, or publicly publish the website program or content.
8.3 Protecting intellectual property rights is your obligation. If there is any violation, you shall be liable for damages.
9.1 In order to provide you with better services, we will update and improve the service from time to time, and timely revise this Agreement. These amendments constitute part of this Agreement and have the same force and effect as this Agreement. Without your explicit consent, we will not reduce your rights under the Agreement as presently in effect.
9.2 If we modify this Agreement, we will announce it in advance through a website announcement and obtain your consent through a pop-up window. If you cannot agree to the content of the modified Agreement, you shall have the right to stop using the relevant services. If you continue to use our services after this policy update takes effect, you will be deemed to have fully read, understood and accepted the updated Agreement, and are willing to be bound by the updated Agreement.
The validity, interpretation, modification, execution, and dispute resolution of this Agreement shall be governed by the laws of the People's Republic of China. This Agreement is written in Chinese and English versions. In case understandings are different, it will be subject to the understanding in Chinese finally. In the event of a dispute arising in the performance of this Agreement, both parties shall negotiate and resolve it. If either party of this Agreement is unwilling to negotiate or the negotiation fails, either party shall have the right to submit the dispute to Shanghai International Economic and Trade Arbitration Commission for arbitration in accordance with the arbitration rules in effect at that time. The arbitration award is final and binding on both parties.
If you have any questions, comments, and suggestions, please contact us through the following contact information:
Email: info@wlalabs.com.cn
We will properly handle your questions. Normally, we will reply within 10 working days after verifying your identity.
Last updated: May 18, 2023
The WLA Labs (hereinafter referred to as "We/us/our") fully respects and protects the privacy of users. We collect, store, protect, use or share your personal information in accordance with this Privacy Policy (hereinafter referred to as "Policy"). We recommend that you read the Policy in its entirety to help you understand how to protect your privacy. In order to make you fully understand the Policy, the terms of the Policy that have or may have a significant impact on your interests have been marked in bold for your attention. By clicking to confirm or start using our services, you will be deemed to have fully understood the Policy and agree that we can use and protect your personal information legally in accordance with the Policy.
When you access our website or use our services, you may voluntarily provide us with personal information and we also collect some of your information. The scope of information we collect depends on the type of service users need, including but not limited to:
1.1. When you apply to register your website account, you need to provide us with relevant personal information, including your name, mobile phone number and email address.
1.2. If you would like to purchase tickets and participate in offline conference activities, you also need to provide us with personal information used for the real-name authentication of citizens, including an ID number, company name, position, and personal photo.
1.3. To protect your account security, when you access our website or use our services, your access data may be recorded automatically, such as your browsing records, visiting date and time, browser information, hardware, and software functions and network link information (IP address, port, network protocol, etc.)
1.4. In addition to the above information, we may collect other information about you for the reasonable purpose of improving the service quality, including information you post on the website, information you provide when contacting our customer service, answers sent to us when taking questionnaires, etc.
Your information is stored on servers located in China. For security and backup purposes, we may store your information and data on storage media that we purchase, lease or otherwise use from a qualified third party (e.g., Alibaba Cloud). In this case, we will require the third party to keep your information strictly confidential. At present, we will not store the above information outside of China. If we transmit and store the information outside of China, we will comply with the relevant national regulations and seek your consent.
We attach great importance to your personal information security, and will endeavor to take reasonable security measures (including technical and management means) to protect your personal information and prevent the personal information provided by you from being accessed, publicly disclosed, used, modified, damaged, lost or leaked inappropriately.
3.1. We protect your personal information with encryption technology, anonymous processing and relevant reasonable and feasible means that are not inferior to those adopted by the industry peers, and use security protection mechanisms to prevent your personal information from being attacked maliciously.
3.2. We set up a special security department, security management system, and data security procedures to protect your personal information security. We implement a strict data usage and access system to ensure that only authorized personnel can access your personal information, and conduct security audits on data and technology in due course.
3.3. Although the above reasonable and effective measures have been taken and the standards required by relevant laws and regulations have been complied with, please be noted that, due to technical limitations and possible malicious means, it is not always possible to ensure 100% security of information in the Internet industry, even if we try our best to strengthen the security measures. We will do our best to ensure the security of the personal information you provide to us.
3.4. We have developed emergency plans and we will immediately launch them in case of users' information security incidents, in an effort to prevent the impact and consequences of these security incidents from expanding. Once a user information security incident occurs, we will promptly inform you of the situation, possible impact of the incident, the disposal measures we have taken or will take, and recommendations that how you can prevent and reduce risks independently in accordance with the requirements of laws and regulations. At the same time, we will report the handling of user information security incidents in accordance with the requirements of regulatory authorities.
3.5. Please be sure to take good care of your login name and other identity information. When you use our services, we will identify you by your login name, email address and other identity information. Once you disclose the above information, you may suffer losses and may bear adverse legal consequences. If you find that your login name or other identity information may or have been leaked, please contact us immediately so that we can take appropriate measures in a timely manner to reduce the corresponding losses.
In accordance with the requirements of national laws and regulations regarding the lawful and reasonable use of personal information, we will use your relevant information for the following purposes:
4.1. To provide you services of video on demand, purchasing tickets and other services, and maintain, and improve the relevant service content.
4.2. To verify the accuracy of the information and if necessary, verify with a third party. For example, verify the identity information you submitted to us with an authentication service organization.
4.3. In order to let you know about the status of our various services, we will push you the conference agenda information, attendance guide or other information.
4.4. To conduct comprehensive statistics, analysis or processing of users' identity information and access information. We may, for publicity or marketing purposes, use or disclose the processed information. For example, we may count new users who have signed up for an account in a certain period of time, and provide push services to these new users.
4.5. To prevent or prohibit illegal activities.
4.6. Other purposes permitted by you.
5.1. If it is necessary to share your information with any third party in order to provide services to you, we will assess the legality, legitimacy and necessity of collecting information by the third party. We will require third parties to protect your information and to strictly comply with all applicable laws, regulations and regulatory requirements. Meanwhile, we will, in accordance with the requirements of laws and regulations, obtain your consent or confirm that the third party has obtained your consent by the way of agreement confirmation, pop-up window reminder, etc.
5.2. If we need to obtain your information from a third party in order to provide services to you, we will ask the third party to state the source of information and guarantee the legality of the information provided; if the personal information processing activities that we need to carry out in order to conduct any business are beyond the scope of original authorization when you provided personal information to the third party, we will obtain your additional explicit consent.
6.1. To make your website access easier, when you visit our site and use our services, we may identify you through a small data file, so as to help you avoid repetitive steps to enter your registration information, or to help you determine the security of your account. These data files may be cookies, flash cookies, or other local storage provided by your browser or associated application (collectively referred to as "cookies").
6.2. Please understand that some of our services can only be implemented by using cookies. If your browser or browser add-on services allow it, you can modify your acceptance settings of cookies or refuse to use cookies, but in some cases, this may affect your ability to access our website and use our services securely.
7.1. In order to provide you with better services, we will update and improve our service in due course, and revise the Policy at the same time. These amendments constitute a part of the Policy itself and have the same legal force as the Policy. Without your explicit consent, we will not reduce your rights under the Policy for the time being in force.
7.2. If we revise the Policy, we will announce it in advance by means of the website announcement, and obtain your consent in the form of a pop-up window. If you don't agree to the revised version, you may stop using relevant services. If you click to confirm and continue to use our services after the revised policy takes effect, you will be deemed to have fully read, understood and accepted the updated policy, and are willing to be bound by the updated policy.
We may be linked to other websites not maintained by us. We do not control and are not responsible for the content of and policies governing the use of those websites not maintained by us. The inclusion of any link to such websites does not imply approval of or endorsement by us of the websites or the content thereof.
If you have any questions, comments, and suggestions, please contact us through the following contact information:
Email: info@wlalabs.com.cn
We will properly handle your questions. Normally, we will reply within 10 working days after verifying your identity.
Last updated: May 18, 2023
You've already registered for this Conference. Please find more details in My Event .Thank you!
You've already registered for this Conference. Please find more details in My Event. Thank you!
Featuring talks by
Prof. Xiao Wang,
MIT / Broad Institute, U.S.A.
Topic: Translating spatial cell atlas to tissue function
Prof. Ling-Ling Chen,
Investigator, CAS Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences (CAS); New Cornerstone Science Laboratory, China
Topic: Lnc-ing RNA processing and function
Chaired by
Prof. Chuan He,
The University of Chicago / HHMI, U.S.A.
Topic: Reversible RNA methylation in gene expression regulation
The session seeks to examine the latest developments in RNA processing, function, and regulation. The speakers will cover diverse topics such as reversible RNA methylation in gene expression regulation, long noncoding RNAs (lncRNAs) processing and function, and spatial translation cell atlas. These lectures will not only present latest fundamental advances on how different RNA species regulate gene expression and impact cellular function, but also present cutting-edge technologies for spatial translation analysis and cellular granule research, highlighting new frontiers in RNA biology. This session offers a unique opportunity for those interested in RNA to learn from experts in the field, gain knowledge of the latest research and developments, and engage in new areas of RNA research and genomics.
Chuan He, Ph.D., is the John T. Wilson Distinguished Service Professor in the Department of Chemistry and Department of Biochemistry and Molecular Biology at the University of Chicago / HHMI. He received his bachelor of science degree in 1994 from the University of Science and Technology of China and his Ph.D. in chemistry from the Massachusetts Institute of Technology in 2000, studying under Professor Stephen J. Lippard. After training as a Damon-Runyon postdoctoral fellow with Professor Gregory L. Verdine at Harvard University, he joined the University of Chicago as an Assistant Professor, rising to Associate Professor in 2008 and Full Professor in 2010. He was selected as an investigator of the Howard Hughes Medical Institute in 2013.
He's research spans a broad range of fields including chemical biology, RNA biology, epigenetics, biochemistry, and genomics. His recent research concerns reversible RNA and DNA methylation in biological regulation. In 2011, his group discovered reversible RNA methylation as a new mechanism of gene expression regulation. His laboratory characterized the RNA m6A methyltransferase complex and several key reader proteins that bind preferentially to m6A-modified RNA and regulate their stability and translation. In 2020, He's laboratory reported prevalent m6A methylation on chromatin-associated regulatory RNAs (carRNAs), which regulates chromatin state and global transcription. The reversible methylation of carRNA controls mammalian and plant development. His laboratory has spearheaded the development of enabling technologies to study the biology of RNA and DNA modifications.
Xiao Wang, Ph.D., is a core institute member of the Broad Institute of MIT and Harvard and an Assistant Professor in the Department of Chemistry at MIT. She started her lab in 2019 to develop and apply new chemical, biophysical, and genomic tools to better understand brain function and dysfunction at the molecular level.
Wang joined the MIT and Broad after conducting postdoctoral research at Stanford University with Professor Karl Deisseroth, where she was a Fellow of the Life Sciences Research Foundation. At Stanford, she developed comprehensive methods for analyzing RNA in intact tissues that merge sequencing with imaging, in order to reveal the locations of various cell types in the brain.
Wang received her B.S. in chemistry and molecular engineering from Peking University in 2010, where she studied with Professor Jian Pei and helped develop fluorescent organic materials. She received her Ph.D. in chemistry from the University of Chicago in 2015, where she elucidated the cellular functions of RNA modifications with Professor Chuan He.
Ling-Ling Chen, Ph.D., carried out doctoral and post-doctoral work in Biomedical Science at UConn Health, USA with Gordon G. Carmichael from 2004 to 2010. She also completed an MBA degree in Management at the UConn Business School in 2009 and was promoted to Assistant Professor in Residence at UConn in 2010. Chen moved to the CAS Center for Excellence in Molecular Cell Science (also known as the Shanghai Institute of Biochemistry and Cell Biology), Chinese Academy of Sciences (CAS) as an independent PI in 2011. She was selected as a Howard Hughes Medical Institute (HHMI) International Research Scholar in 2017 and as a New Cornerstone Investigator in 2023.
Chen studies RNA biology with a particular focus on long noncoding RNAs (lncRNAs), a giant and varied class of new RNA molecules. Her group has developed methods for genome-wide discovery and characterization of non-polyadenylated RNAs. This work has led to the identification of novel RNA species including broadly expressed circular RNAs and sno-processed lncRNAs. Importantly, these RNAs have been implicated in gene regulation networks and in diseases. Her group now investigates the biogenesis of these RNAs and their mechanisms of action in human health and disease.
Chen serves the community as an advisory board member of many journals including Science, Cell, and Molecular Cell, and as an organizer of several international meetings including the Annual Meeting of the RNA Society, the CSHL Regulatory & Non-coding RNAs, the Keystone Noncoding RNAs and others. She is the recipient of the CBIS Young Investigator Award 2016, the L'Oréal China for Women in Science Award 2016, the Xplorer Prize 2020, the RNA Society Mid-Career Research Award 2021, and etc.
Reversible RNA methylation in gene expression regulation
Prof. Chuan He
Department of Chemistry, Department of Biochemistry and Molecular Biology, Institute for Biophysical Dynamics, Howard Hughes Medical Institute, The University of Chicago
Over 150 types of post-transcriptional RNA modifications have been identified in all kingdoms of life. We have discovered two RNA demethylases, FTO and ALKBH5, which catalyze oxidative demethylation of the most prevalent modifications of mammalian messenger RNA (mRNA) and other nuclear RNA, N6-methyladenosine (m6A). These findings indicate that reversible RNA modification could impact biological regulation analogous to the well-known reversible DNA and histone chemical modifications. We have also characterized proteins that selectively recognize m6A-modified mRNA and affect the translation status and lifetime of the target mRNA. Functional studies reveal m6A methylation as a critical mechanism to group transcripts for coordinated metabolism, translation, and decay, allowing timely and coordinated protein synthesis and transcriptome switching during cell differentiation and development. I will present our recent work elucidating transcriptional regulation through m6A methylation and demethylation, and impacts of this regulation on mammalian early development as well as plant growth.
Lnc-ing RNA processing and function
Prof. Ling-Ling Chen
New Cornerstone Science Laboratory, CAS Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences (CAS)
Long noncoding RNAs (lncRNAs) are emerging as new regulators in gene expression networks and exhibit a surprising range of shapes and sizes. Many lncRNAs are transcribed by RNA polymerase II and are capped, polyadenylated, and spliced like mRNAs. By developing methods for genome-wide discovery and characterization of non-polyadenylated RNAs, we have identified several RNA species with unexpected formats. These RNAs are derived from long primary transcripts via unusual RNA processing pathways and are stabilized by distinct mechanisms, including capping by small nucleolar RNA (snoRNA)–protein (snoRNP) complexes at their ends (sno-lncRNAs) or forming circular structures. We have shown that sno-lncRNAs and circular RNAs are involved in key gene regulation events and are implicated in Pradier-Will syndrome and autoimmune diseases. In this talk, I will discuss the mechanisms of their formation and function, as well as how we study one sno-lncRNA (SLERT) that has enabled us to uncover previously unknown organization and regulation in the human nucleolus.
Translating spatial cell atlas to tissue function
Prof. Xiao Wang
Department of Chemistry, Broad Institute, MIT
Spatially charting molecular cell types at single-cell resolution across the entire three-dimensional (3D) volume of the brain is critical to illustrating the molecular basis of the tissue anatomy and functions. Recent development of spatial transcriptomic methods has enabled scalable profiling of transcriptome-defined spatial cell atlas. Yet, there is still a big gap between spatial cell atlas and tissue function. In this presentation, I will introduce a few experimental and computational advances in our lab that further enable multi-modality deep profiling of cell types and states in situ, bridging single-cell molecular profiles with single-cell functional status in intact biological tissues and accelerating gene-to-function discoveries in development and diseases.